Fujifilm GFX 100S II vs Nikon D80
The Fujifilm GFX 100S II and the Nikon D80 are two digital cameras that were officially introduced, respectively, in May 2024 and August 2006. The GFX 100S II is a mirrorless interchangeable lens camera, while the D80 is a DSLR. The cameras are based on a medium format (GFX 100S II) and an APS-C (D80) sensor. The Fujifilm has a resolution of 101.8 megapixels, whereas the Nikon provides 10 MP.
Below is an overview of the main specs of the two cameras as a starting point for the comparison.

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Going beyond this snapshot of core features and characteristics, what are the differences between the Fujifilm GFX 100S II and the Nikon D80? Which one should you buy? Read on to find out how these two cameras compare with respect to their body size, their imaging sensors, their shooting features, their input-output connections, and their reception by expert reviewers.
Body comparison
The physical size and weight of the Fujifilm GFX 100S II and the Nikon D80 are illustrated in the side-by-side display below. The two cameras are presented according to their relative size. Three consecutive views from the front, the top, and the rear side are shown. All width, height and depth measures are rounded to the nearest millimeter.



If the front view area (width x height) of the cameras is taken as an aggregate measure of their size, the Nikon D80 is notably smaller (13 percent) than the Fujifilm GFX 100S II. Moreover, the D80 is markedly lighter (24 percent) than the GFX 100S II. It is worth mentioning in this context that the GFX 100S II is splash and dust resistant, while the D80 does not feature any corresponding weather-sealing.
The above size and weight comparisons are to some extent incomplete since they do not consider the interchangeable lenses that both of these cameras require. Hence, you might want to study and compare the specifications of available lenses in order to get the full picture of the size and weight of the two camera systems.
Concerning battery life, the GFX 100S II gets 530 shots out of its Fujifilm NP-W235 battery, while the D80 can take 600 images on a single charge of its Nikon EN-EL3e power pack. The power pack in the GFX 100S II can be charged via the USB port, so that it is not always necessary to take the battery charger along when travelling.
The following table provides a synthesis of the main physical specifications of the two cameras and other similar ones. If you would like to visualize and compare a different camera combination, you can navigate to the CAM-parator app and make your selection from a broad list of cameras there.

| Camera Model |
Camera Width |
Camera Height |
Camera Depth |
Camera Weight |
Battery Life |
Weather Sealing |
Camera Launch |
Launch Price |
Street Price |
||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. | Fujifilm GFX 100S II | 150 mm | 104 mm | 87 mm | 883 g | 530 | Y | May 2024 | US$ 4 999 | amazon.com | |
| 2. | Nikon D80 | 132 mm | 103 mm | 77 mm | 668 g | 600 | n | Aug 2006 | US$ 999 | ebay.com | |
| 3. | Canon R3 | 150 mm | 143 mm | 87 mm | 1015 g | 760 | Y | Sep 2021 | US$ 5 999 | amazon.com | |
| 4. | Canon R5 Mark II | 138 mm | 98 mm | 88 mm | 746 g | 340 | Y | Jul 2024 | US$ 4 299 | amazon.com | |
| 5. | Fujifilm GFX 50R | 161 mm | 97 mm | 66 mm | 775 g | 400 | Y | Sep 2018 | US$ 4 499 | ebay.com | |
| 6. | Fujifilm GFX 50S II | 150 mm | 104 mm | 87 mm | 900 g | 440 | Y | Sep 2021 | US$ 3 999 | amazon.com | |
| 7. | Fujifilm GFX 100 | 156 mm | 144 mm | 75 mm | 1320 g | 800 | Y | May 2019 | US$ 9 999 | ebay.com | |
| 8. | Fujifilm GFX 100 II | 152 mm | 117 mm | 99 mm | 1030 g | 540 | Y | Sep 2023 | US$ 7 499 | amazon.com | |
| 9. | Fujifilm GFX 100RF | 134 mm | 90 mm | 77 mm | 735 g | 820 | Y | Mar 2025 | US$ 4 899 | amazon.com | |
| 10. | Fujifilm GFX 100S | 150 mm | 104 mm | 87 mm | 900 g | 460 | Y | Jan 2021 | US$ 5 999 | amazon.com | |
| 11. | Hasselblad X2D 100C | 149 mm | 106 mm | 75 mm | 895 g | 420 | Y | Sep 2022 | US$ 8 199 | amazon.com | |
| 12. | Leica SL3-S | 141 mm | 108 mm | 85 mm | 852 g | 315 | Y | Jan 2025 | US$ 5 299 | amazon.com | |
| 13. | Nikon D50 | 133 mm | 102 mm | 76 mm | 620 g | 400 | n | Apr 2005 | US$ 749 | ebay.com | |
| 14. | Nikon D70 | 140 mm | 111 mm | 78 mm | 679 g | 400 | n | Jan 2004 | US$ 999 | ebay.com | |
| 15. | Nikon D70s | 140 mm | 111 mm | 78 mm | 679 g | 500 | n | Apr 2005 | US$ 899 | ebay.com | |
| 16. | Nikon D90 | 132 mm | 103 mm | 77 mm | 703 g | 850 | n | Aug 2008 | US$ 1 299 | ebay.com | |
| 17. | Nikon D5000 | 127 mm | 104 mm | 80 mm | 590 g | 510 | n | Apr 2009 | US$ 749 | ebay.com | |
| Note: Measurements and pricing do not include easily detachable parts, such as add-on or interchangeable lenses or optional viewfinders. | |||||||||||
Any camera decision will obviously take relative prices into account. The retail prices at the time of the camera’s release place the model in the market relative to other models in the producer’s line-up and the competition. The D80 was launched at a markedly lower price (by 80 percent) than the GFX 100S II, which puts it into a different market segment. Usually, retail prices stay at first close to the launch price, but after several months, discounts become available. Later in the product cycle and, in particular, when the replacement model is about to appear, further discounting and stock clearance sales often push the camera price considerably down. Then, after the new model is out, very good deals can frequently be found on the pre-owned market.
Sensor comparison
The imaging sensor is at the core of digital cameras and its size is one of the main determining factors of image quality. A large sensor will generally have larger individual pixels that offer better low-light sensitivity, provide wider dynamic range, and have richer color-depth than smaller pixels in a sensor of the same technological generation. Furthermore, a large sensor camera will give the photographer more possibilities to use shallow depth-of-field in order to isolate a subject from the background. On the downside, larger sensors are more costly to manufacture and tend to lead to bigger and heavier cameras and lenses.
Of the two cameras under consideration, the Fujifilm GFX 100S II features a medium format sensor and the Nikon D80 an APS-C sensor. The sensor area in the D80 is 74 percent smaller. As a result of these sensor size differences, the cameras have a format factor of, respectively, 0.79 and 1.5. The sensor in the GFX 100S II has a native 4:3 aspect ratio, while the one in the D80 offers a 3:2 aspect.

With 101.8MP, the GFX 100S II offers a higher resolution than the D80 (10MP), but the GFX 100S II has smaller individual pixels (pixel pitch of 3.76μm versus 6.11μm for the D80). However, the GFX 100S II is a much more recent model (by 17 years and 9 months) than the D80, and its sensor will have benefitted from technological advances during this time that enhance the light gathering capacity of its pixels. Coming back to sensor resolution, it should be mentioned that the GFX 100S II has no anti-alias filter installed, so that it can capture all the detail its sensor resolves.
The resolution advantage of the Fujifilm GFX 100S II implies greater flexibility for cropping images or the possibility to print larger pictures. The maximum print size of the GFX 100S II for good quality output (200 dots per inch) amounts to 58.2 x 43.7 inches or 147.9 x 110.9 cm, for very good quality (250 dpi) 46.6 x 34.9 inches or 118.3 x 88.8 cm, and for excellent quality (300 dpi) 38.8 x 29.1 inches or 98.6 x 74 cm. The corresponding values for the Nikon D80 are 19.4 x 13 inches or 49.2 x 32.9 cm for good quality, 15.5 x 10.4 inches or 39.3 x 26.3 cm for very good quality, and 12.9 x 8.6 inches or 32.8 x 21.9 cm for excellent quality prints.
The GFX 100S II has on-sensor phase detect pixels, which results in fast and reliable autofocus acquisition even during live view operation.
Unlike the D80, the GFX 100S II has the capacity to capture high quality composite images (YESMP) by combining multiple shots after shifting its sensor by miniscule distances. This multi-shot, pixel-shift mode is most suitable for photography of stationary objects (landscapes, studio scenes).
The Fujifilm GFX 100S II has a native sensitivity range from ISO 100 to ISO 12800, which can be extended to ISO 50-102400. The corresponding ISO settings for the Nikon D80 are ISO 100 to ISO 1600, with the possibility to increase the ISO range to 100-3200.
In terms of underlying technology, the GFX 100S II is build around a BSI-CMOS sensor, while the D80 uses a CCD imager. Both cameras use a Bayer filter for capturing RGB colors on a square grid of photosensors. This arrangement is found in most digital cameras.

Since 2007, DXO Mark has published sensor performance measurements that have been derived using a consistent methodology. This service determines an overall sensor rating, as well as sub-scores for low-light sensitivity ("DXO Sports"), dynamic range ("DXO Landscape"), and color depth ("DXO Portrait"). The adjacent table reports on the physical sensor characteristics and the outcomes of the DXO sensor quality tests for a sample of comparator-cameras.

| Camera Model |
Sensor Class |
Resolution (MP) |
Horiz. Pixels |
Vert. Pixels |
Video Format |
DXO Portrait |
DXO Landscape |
DXO Sports |
DXO Overall |
||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. | Fujifilm GFX 100S II | Medium Format | 101.8 | 11648 | 8736 | 4K/30p | 25.9 | 15.1 | 3720 | 101 | |
| 2. | Nikon D80 | APS-C | 10.0 | 3872 | 2592 | none | 22.1 | 11.2 | 524 | 61 | |
| 3. | Canon R3 | Full Frame | 24.0 | 6000 | 4000 | 6K/60p | 25.0 | 14.7 | 4086 | 96 | |
| 4. | Canon R5 Mark II | Full Frame | 44.8 | 8192 | 5464 | 8k/60p | 25.4 | 14.8 | 3332 | 97 | |
| 5. | Fujifilm GFX 50R | Medium Format | 51.1 | 8256 | 6192 | 1080/30p | 25.7 | 14.4 | 3169 | 98 | |
| 6. | Fujifilm GFX 50S II | Medium Format | 51.1 | 8256 | 6192 | 1080/30p | 25.9 | 14.8 | 3456 | 100 | |
| 7. | Fujifilm GFX 100 | Medium Format | 101.8 | 11648 | 8736 | 4K/30p | 25.7 | 14.5 | 3227 | 99 | |
| 8. | Fujifilm GFX 100 II | Medium Format | 101.8 | 11648 | 8736 | 8K/30p | 25.9 | 15.0 | 3651 | 101 | |
| 9. | Fujifilm GFX 100RF | Medium Format | 101.8 | 11648 | 8736 | 4K/30p | 25.9 | 15.1 | 3805 | 101 | |
| 10. | Fujifilm GFX 100S | Medium Format | 101.8 | 11648 | 8736 | 4K/30p | 25.8 | 14.7 | 3391 | 100 | |
| 11. | Hasselblad X2D 100C | Medium Format | 102.1 | 11656 | 8762 | none | 25.9 | 14.9 | 3550 | 101 | |
| 12. | Leica SL3-S | Full Frame | 24.0 | 6000 | 4000 | 6K/30p | 25.4 | 14.8 | 3383 | 97 | |
| 13. | Nikon D50 | APS-C | 6.0 | 3008 | 2000 | none | 20.9 | 10.8 | 560 | 55 | |
| 14. | Nikon D70 | APS-C | 6.0 | 3008 | 2000 | none | 20.4 | 10.3 | 529 | 50 | |
| 15. | Nikon D70s | APS-C | 6.0 | 3008 | 2000 | none | 20.4 | 10.3 | 529 | 50 | |
| 16. | Nikon D90 | APS-C | 12.2 | 4288 | 2848 | 720/24p | 22.7 | 12.5 | 977 | 73 | |
| 17. | Nikon D5000 | APS-C | 12.2 | 4288 | 2848 | 720/24p | 22.7 | 12.5 | 868 | 72 | |
| Note: DXO values in italics represent estimates based on sensor size and age. | |||||||||||
Many modern cameras are not only capable of taking still images, but can also record movies. The GFX 100S II indeed provides movie recording capabilities, while the D80 does not. The highest resolution format that the GFX 100S II can use is 4K/30p.
Feature comparison
Apart from body and sensor, cameras can and do differ across a variety of features. For example, the GFX 100S II has an electronic viewfinder (5760k dots), while the D80 has an optical one. Both systems have their advantages, with the electronic viewfinder making it possible to project supplementary shooting information into the framing view, whereas the optical viewfinder offers lag-free viewing and a very clear framing image. The viewfinder in the GFX 100S II offers a wider field of view (100%) than the one in the D80 (95%), so that a larger proportion of the captured image is visible in the finder. In addition, the viewfinder of the GFX 100S II has a higher magnification (0.84x vs 0.62x), so that the size of the image transmitted appears closer to the size seen with the naked human eye. The table below summarizes some of the other core capabilities of the Fujifilm GFX 100S II and Nikon D80 in connection with corresponding information for a sample of similar cameras.

| Camera Model |
Viewfinder (Type or 000 dots) |
Control Panel (yes/no) |
LCD Specifications (inch/000 dots) |
LCD Attach- ment |
Touch Screen (yes/no) |
Max Shutter Speed * |
Max Shutter Flaps * |
Built-in Flash (yes/no) |
Built-in Image Stab |
||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. | Fujifilm GFX 100S II | 5760 | Y | 3.2 / 2360 | full-flex | Y | 1/4000s | 7.0/s | n | Y | |
| 2. | Nikon D80 | optical | n | 2.5 / 230 | fixed | n | 1/4000s | 3.0/s | Y | n | |
| 3. | Canon R3 | 5760 | Y | 3.2 / 4150 | swivel | Y | 1/8000s | 12.0/s | n | Y | |
| 4. | Canon R5 Mark II | 5760 | Y | 3.2 / 2100 | swivel | Y | 1/8000s | 12.0/s | n | Y | |
| 5. | Fujifilm GFX 50R | 3690 | n | 3.2 / 2360 | tilting | Y | 1/4000s | 3.0/s | n | n | |
| 6. | Fujifilm GFX 50S II | 3690 | Y | 3.2 / 2360 | full-flex | Y | 1/4000s | 3.0/s | n | Y | |
| 7. | Fujifilm GFX 100 | optional | Y | 3.2 / 2360 | full-flex | Y | 1/4000s | 5.0/s | n | Y | |
| 8. | Fujifilm GFX 100 II | 9440 | Y | 3.2 / 2360 | full-flex | Y | 1/4000s | 8.0/s | n | Y | |
| 9. | Fujifilm GFX 100RF | 5760 | n | 3.2 / 2100 | tilting | Y | 1/4000s | 6.0/s | n | n | |
| 10. | Fujifilm GFX 100S | 3690 | Y | 3.2 / 2360 | full-flex | Y | 1/4000s | 5.0/s | n | Y | |
| 11. | Hasselblad X2D 100C | 5760 | Y | 3.6 / 2360 | tilting | Y | 1/4000s | 3.3/s | n | Y | |
| 12. | Leica SL3-S | 5760 | Y | 3.2 / 2333 | tilting | Y | 1/8000s | 30.0/s | n | Y | |
| 13. | Nikon D50 | optical | n | 2.0 / 130 | fixed | n | 1/4000s | 2.5/s | Y | n | |
| 14. | Nikon D70 | optical | n | 1.8 / 130 | fixed | n | 1/8000s | 3.0/s | Y | n | |
| 15. | Nikon D70s | optical | n | 2.0 / 130 | fixed | n | 1/8000s | 3.0/s | Y | n | |
| 16. | Nikon D90 | optical | Y | 3.0 / 920 | fixed | n | 1/4000s | 4.5/s | Y | n | |
| 17. | Nikon D5000 | optical | n | 2.7 / 230 | full-flex | n | 1/4000s | 4.0/s | Y | n | |
| Note: *) Information refers to the mechanical shutter, unless the camera only has an electronic one. | |||||||||||
One feature that is present on the GFX 100S II, but is missing on the D80 is a top-level LCD. While being, of course, smaller than the rear screen, the control panel conveys some of the essential shooting information and can be convenient for quick and easy settings verification.
The reported shutter speed information refers to the use of the mechanical shutter. Yet, some cameras only have an electronic shutter, while others have an electronic shutter in addition to a mechanical one. In fact, the GFX 100S II is one of those camera that have an additional electronic shutter, which makes completely silent shooting possible. However, this mode is less suitable for photographing moving objects (risk of rolling shutter) or shooting under artificial light sources (risk of flickering).
The Fujifilm GFX 100S II has an intervalometer built-in. This enables the photographer to capture time lapse sequences, such as flower blooming, a sunset or moon rise, without purchasing an external camera trigger and related software.
The GFX 100S II writes its imaging data to SDXC cards, while the D80 uses SDHC cards. The GFX 100S II features dual card slots, which can be very useful in case a memory card fails. In contrast, the D80 only has one slot. The GFX 100S II supports UHS-II cards (on both slots), while the D80 cannot take advantage of Ultra High Speed SD cards.
Connectivity comparison
For some imaging applications, the extent to which a camera can communicate with its environment can be an important aspect in the camera decision process. The table below provides an overview of the connectivity of the Fujifilm GFX 100S II and Nikon D80 and, in particular, the interfaces the cameras (and selected comparators) provide for accessory control and data transfer.

| Camera Model |
Hotshoe Port |
Internal Mic / Speaker |
Microphone Port |
Headphone Port |
HDMI Port |
USB Port |
WiFi Support |
NFC Support |
Bluetooth Support |
||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. | Fujifilm GFX 100S II | Y | stereo / mono | Y | Y | micro | 3.2 | Y | - | Y | |
| 2. | Nikon D80 | Y | - / - | - | - | - | 2.0 | - | - | - | |
| 3. | Canon R3 | Y | stereo / mono | Y | Y | micro | 3.2 | Y | - | Y | |
| 4. | Canon R5 Mark II | Y | mono / mono | Y | Y | full | 3.2 | Y | - | Y | |
| 5. | Fujifilm GFX 50R | Y | stereo / mono | Y | Y | micro | 3.0 | Y | - | Y | |
| 6. | Fujifilm GFX 50S II | Y | stereo / mono | Y | Y | micro | 3.2 | Y | - | - | |
| 7. | Fujifilm GFX 100 | Y | stereo / mono | Y | Y | micro | 3.1 | Y | - | Y | |
| 8. | Fujifilm GFX 100 II | Y | stereo / mono | Y | Y | full | 3.2 | Y | - | Y | |
| 9. | Fujifilm GFX 100RF | Y | stereo / mono | Y | Y | micro | 3.2 | Y | - | Y | |
| 10. | Fujifilm GFX 100S | Y | stereo / mono | Y | Y | micro | 3.2 | Y | - | Y | |
| 11. | Hasselblad X2D 100C | Y | stereo / mono | - | - | - | 3.2 | Y | - | - | |
| 12. | Leica SL3-S | Y | stereo / mono | Y | Y | full | 3.2 | Y | - | Y | |
| 13. | Nikon D50 | Y | - / - | - | - | - | 2.0 | - | - | - | |
| 14. | Nikon D70 | Y | - / - | - | - | - | 1.0 | - | - | - | |
| 15. | Nikon D70s | Y | - / - | - | - | - | 2.0 | - | - | - | |
| 16. | Nikon D90 | Y | mono / mono | - | - | mini | 2.0 | - | - | - | |
| 17. | Nikon D5000 | Y | mono / mono | - | - | mini | 2.0 | - | - | - |
It is notable that the GFX 100S II offers wifi support, while the D80 does not. Wifi can be a very convenient means to transfer image data to an off-camera location.
Studio photographers will appreciate that the Fujifilm GFX 100S II (unlike the D80) features a PC Sync socket, so that professional strobe lights can be controlled by the camera.
The GFX 100S II is a recent model that features in the current product line-up of Fujifilm. In contrast, the D80 has been discontinued (but can be found pre-owned on ebay). As a replacement in the same line of cameras, the D80 was succeeded by the Nikon D90. Further information on the two cameras (e.g. user guides, manuals), as well as related accessories, can be found on the official Fujifilm and Nikon websites.
Review summary
So how do things add up? Is there a clear favorite between the Fujifilm GFX 100S II and the Nikon D80? Which camera is better? The listing below highlights the relative strengths of the two models.

Advantages of the Fujifilm GFX 100S II:
- More detail: Offers more megapixels (101.8 vs 10MP) with a 213% higher linear resolution.
- Maximized detail: Lacks an anti-alias filter to exploit the sensor's full resolution potential.
- High quality composites: Can combine several shots after pixel-shifting its sensor.
- Better image quality: Features a larger and more technologically advanced imaging sensor.
- Richer colors: The sensor size advantage translates into images with better, more accurate colors.
- More dynamic range: Larger sensor captures a wider spectrum of light and dark details.
- Better low-light sensitivity: Larger sensor produces good images even in poorly lit environments.
- Broader imaging potential: Can record not only still images but also 4K/30p movies.
- Better live-view autofocus: Features on-sensor phase-detection for more confident autofocus.
- More framing info: Has an electronic viewfinder that displays shooting data.
- More complete view: Has a viewfinder with a larger field of view (100% vs 95%).
- Larger viewfinder image: Features a viewfinder with a higher magnification (0.84x vs 0.62x).
- Easier setting verification: Features an LCD display on top to control shooting parameters.
- Larger screen: Has a bigger rear LCD (3.2" vs 2.5") for image review and settings control.
- More detailed LCD: Has a higher resolution rear screen (2360k vs 230k dots).
- More flexible LCD: Has a full-flex screen for odd-angle shots in portrait or landscape orientation.
- Fewer buttons to press: Is equipped with a touch-sensitive rear screen to facilitate handling.
- Faster burst: Shoots at higher frequency (7 vs 3 flaps/sec) to capture the decisive moment.
- Less disturbing: Has an electronic shutter option for completely silent shooting.
- Easier time-lapse photography: Has an intervalometer built-in for low frequency shooting.
- Easier travel charging: Can be conveniently charged via its USB port.
- Better sealing: Is weather sealed to enable shooting in dusty or wet environments.
- Sharper images: Has hand-shake reducing image stabilization built-in.
- More legacy lens friendly: Can take a broad range of non-native lenses via adapters.
- Faster data transfer: Supports a more advanced USB protocol (3.2 vs 2.0).
- Easier file upload: Has wifi built in for automatic backup or image transfer to the web.
- Easier wireless transfer: Supports Bluetooth for image sharing without cables.
- Better studio light control: Has a PC Sync socket to connect to professional strobe lights.
- Greater peace of mind: Features a second card slot as a backup in case of memory card failure.
- Faster buffer clearing: Supports Ultra High Speed (UHS-II) SDXC cards on both slots.
- More modern: Reflects 17 years and 9 months of technical progress since the D80 launch.

Reasons to prefer the Nikon D80:
- Better moiré control: Has an anti-alias filter to avoid artificial patterns to appear in images.
- Brighter framing: Features an optical viewfinder for clear, lag-free composition.
- More compact: Is smaller (132x103mm vs 150x104mm) and will fit more readily into a bag.
- Less heavy: Has a lower weight (by 215g or 24 percent) and is thus easier to take along.
- Longer lasting: Gets more shots (600 versus 530) out of a single battery charge.
- Easier fill-in: Has a small integrated flash to brighten shadows of backlit subjects.
- More affordable: Was introduced into a lower priced category (80 percent cheaper at launch).
- More heavily discounted: Has been around for much longer (launched in August 2006).
If the count of individual advantages (bullet points above) is taken as a guide, the GFX 100S II is the clear winner of the match-up (31 : 8 points). However, the relative importance of the various individual camera aspects will vary according to personal preferences and needs, so that you might like to apply corresponding weights to the particular features before making a decision on a new camera. A professional wildlife photographer will view the differences between cameras in a way that diverges from the perspective of a family photog, and a person interested in architecture has distinct needs from a sports shooter. Hence, the decision which camera is best and worth buying is often a very personal one.
How about other alternatives? Do the specifications of the Fujifilm GFX 100S II and the Nikon D80 place the cameras among the top in their class? Find out in the latest Best Mirrorless Interchangeable Lens Camera and Best DSLR Camera listings whether the two cameras rank among the cream of the crop.
In any case, while the comparison of the spec-sheets of cameras can offer a general idea of their imaging potential, it remains incomplete and does no justice, for example, to the way the GFX 100S II or the D80 perform in practice. At times, user reviews, such as those published at amazon, address these issues in a useful manner, but such feedback is on many occasions incomplete, inconsistent, and unreliable.
Expert reviews
This is why hands-on reviews by experts are important. The adjacent summary-table relays the overall verdicts of several of the most popular camera review sites (amateurphotographer [AP], cameralabs [CL], digitalcameraworld [DCW], dpreview [DPR], ephotozine [EPZ], photographyblog [PB]). As can be seen, the professional reviewers agree in many cases on the quality of different cameras, but sometimes their assessments diverge, reinforcing the earlier point that a camera decision is often a very personal choice.

| Camera Model |
AP score |
CL score |
DCW score |
DPR score |
EPZ score |
PB score |
Camera Launch |
Launch Price |
Street Price |
||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. | Fujifilm GFX 100S II | .. | .. | .. | .. | .. | .. | May 2024 | US$ 4 999 | amazon.com | |
| 2. | Nikon D80 | .. | + | .. | + + | o | 4.5/5 | Aug 2006 | US$ 999 | ebay.com | |
| 3. | Canon R3 | 5/5 | o | 4.5/5 | .. | 5/5 | 4.5/5 | Sep 2021 | US$ 5 999 | amazon.com | |
| 4. | Canon R5 Mark II | .. | .. | .. | 93/100 | .. | .. | Jul 2024 | US$ 4 299 | amazon.com | |
| 5. | Fujifilm GFX 50R | 5/5 | .. | 5/5 | 84/100 | 4.5/5 | 4.5/5 | Sep 2018 | US$ 4 499 | ebay.com | |
| 6. | Fujifilm GFX 50S II | 5/5 | .. | 5/5 | 87/100 | .. | 5/5 | Sep 2021 | US$ 3 999 | amazon.com | |
| 7. | Fujifilm GFX 100 | 4.5/5 | + + | 4.8/5 | 90/100 | 5/5 | 4.5/5 | May 2019 | US$ 9 999 | ebay.com | |
| 8. | Fujifilm GFX 100 II | 5/5 | + | 5/5 | .. | .. | 4.5/5 | Sep 2023 | US$ 7 499 | amazon.com | |
| 9. | Fujifilm GFX 100RF | .. | .. | .. | .. | .. | .. | Mar 2025 | US$ 4 899 | amazon.com | |
| 10. | Fujifilm GFX 100S | 5/5 | + + | 5/5 | 90/100 | 5/5 | 5/5 | Jan 2021 | US$ 5 999 | amazon.com | |
| 11. | Hasselblad X2D 100C | 4/5 | .. | 5/5 | .. | .. | .. | Sep 2022 | US$ 8 199 | amazon.com | |
| 12. | Leica SL3-S | .. | .. | .. | .. | .. | .. | Jan 2025 | US$ 5 299 | amazon.com | |
| 13. | Nikon D50 | .. | 78/100 | .. | + + | 4/5 | 4.5/5 | Apr 2005 | US$ 749 | ebay.com | |
| 14. | Nikon D70 | .. | .. | .. | + + | .. | .. | Jan 2004 | US$ 999 | ebay.com | |
| 15. | Nikon D70s | .. | .. | .. | .. | .. | 5/5 | Apr 2005 | US$ 899 | ebay.com | |
| 16. | Nikon D90 | .. | + + | .. | + + | 4/5 | 4.5/5 | Aug 2008 | US$ 1 299 | ebay.com | |
| 17. | Nikon D5000 | .. | + + | .. | 75/100 | 4/5 | 4.5/5 | Apr 2009 | US$ 749 | ebay.com | |
| Note: (+ +) highly recommended; (+) recommended; (o) reviewed; (..) not available. | |||||||||||
Care should be taken when interpreting the review scores above, though. The ratings were established in reference to similarly priced cameras that were available in the market at the time of the review. Hence, a score should always be seen in the context of the camera's market launch date and its price, and comparisons of ratings among very different cameras or across long time periods have little meaning. It should also be noted that some of the review sites have over time altered the way they render their verdicts.

Check GFX 100S II price at
amazon.com

Check D80 offers at
ebay.com
Other camera comparisons
Did this review help to inform your camera decision process? In case you are interested in seeing how other cameras pair up, just make a corresponding selection in the search boxes below. Alternatively, you can follow any of the listed hyperlinks for comparisons that others found interesting.
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Specifications: Fujifilm GFX 100S II vs Nikon D80
Below is a side-by-side comparison of the specs of the two cameras to facilitate a quick review of their differences and common features.
| Camera Model | Fujifilm GFX 100S II | Nikon D80 |
|---|---|---|
| Camera Type | Mirrorless system camera | Digital single lens reflex |
| Camera Lens | Fujifilm G mount lenses | Nikon F mount lenses |
| Launch Date | May 2024 | August 2006 |
| Launch Price | USD 4,999 | USD 999 |
| Sensor Specs | Fujifilm GFX 100S II | Nikon D80 |
| Sensor Technology | BSI-CMOS | CCD |
| Sensor Format | Medium Format Sensor | APS-C Sensor |
| Sensor Size | 43.8 x 32.9 mm | 23.6 x 15.8 mm |
| Sensor Area | 1441.02 mm2 | 372.88 mm2 |
| Sensor Diagonal | 54.8 mm | 28.4 mm |
| Crop Factor | 0.79x | 1.5x |
| Sensor Resolution | 101.8 Megapixels | 10 Megapixels |
| Image Resolution | 11648 x 8736 pixels | 3872 x 2592 pixels |
| Pixel Pitch | 3.76 μm | 6.11 μm |
| Pixel Density | 7.06 MP/cm2 | 2.69 MP/cm2 |
| Moiré control | no AA filter | Anti-Alias filter |
| Movie Capability | 4K/30p Video | no Video |
| ISO Setting | 100 - 12,800 ISO | 100 - 1,600 ISO |
| ISO Boost | 50 - 102,400 ISO | 100 - 3,200 ISO |
| DXO Sensor Quality (score) | .. | 61 |
| DXO Color Depth (bits) | .. | 22.1 |
| DXO Dynamic Range (EV) | .. | 11.2 |
| DXO Low Light (ISO) | .. | 524 |
| Screen Specs | Fujifilm GFX 100S II | Nikon D80 |
| Viewfinder Type | Electronic viewfinder | Optical viewfinder |
| Viewfinder Field of View | 100% | 95% |
| Viewfinder Magnification | 0.84x | 0.62x |
| Viewfinder Resolution | 5760k dots | |
| Top-Level Screen | Control Panel | no Top Display |
| LCD Framing | Live View | |
| Rear LCD Size | 3.2inch | 2.5inch |
| LCD Resolution | 2360k dots | 230k dots |
| LCD Attachment | Fully flexible screen | Fixed screen |
| Touch Input | Touchscreen | no Touchscreen |
| Shooting Specs | Fujifilm GFX 100S II | Nikon D80 |
| Focus System | On-Sensor Phase-detect | Phase-detect AF |
| Manual Focusing Aid | Focus Peaking | no Peaking Feature |
| Continuous Shooting | 7 shutter flaps/s | 3 shutter flaps/s |
| Electronic Shutter | up to 1/32000s | no E-Shutter |
| Time-Lapse Photography | Intervalometer built-in | no Intervalometer |
| Image Stabilization | In-body stabilization | Lens stabilization only |
| Fill Flash | no On-Board Flash | Built-in Flash |
| Storage Medium | SDXC cards | SDHC cards |
| Single or Dual Card Slots | Dual card slots | Single card slot |
| UHS card support | Dual UHS-II | no |
| Connectivity Specs | Fujifilm GFX 100S II | Nikon D80 |
| External Flash | Hotshoe | Hotshoe |
| Studio Flash | PC Sync socket | no PC Sync |
| USB Connector | USB 3.2 | USB 2.0 |
| HDMI Port | micro HDMI | no HDMI |
| Microphone Port | External MIC port | no MIC socket |
| Headphone Socket | Headphone port | no Headphone port |
| Wifi Support | Wifi built-in | no Wifi |
| Bluetooth Support | Bluetooth built-in | no Bluetooth |
| Body Specs | Fujifilm GFX 100S II | Nikon D80 |
| Environmental Sealing | Weathersealed body | not weather sealed |
| Battery Type | Fujifilm NP-W235 | Nikon EN-EL3e |
| Battery Life (CIPA) | 530 shots per charge | 600 shots per charge |
| In-Camera Charging | USB charging | no USB charging |
| Body Dimensions |
150 x 104 x 87 mm (5.9 x 4.1 x 3.4 in) |
132 x 103 x 77 mm (5.2 x 4.1 x 3.0 in) |
| Camera Weight | 883 g (31.1 oz) | 668 g (23.6 oz) |

Check GFX 100S II price at
amazon.com

Check D80 offers at
ebay.com
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